• News
  • May 12, 2016
  • Anitoa Introduces Portable Chemiluminescence Imager using CIS Technology

  • May 6, 2015
  • Anitoa Systems Demonstrates Compact qPCR with Ultra Low-Light CMOS Bio-Optical Sensor

  • Oct. 1, 2014
  • Anitoa introduces world's most sensitive CMOS bio-optical sensor, capable of 3e-6 lux detection threshold, enabling portable medical and scientific instruments

    • Motivations
    • Lack of effective diagnostics is a leading cause of millions of lives lost to infectious diseases each year. Countless patients around the world also contract secondary infections from blood transfusion and other clinical contacts due to insufficient screening for the surging drug-resistant bacterial or viral pathogens. There is now an urgent need for portable, precise and globally affordable diagnostics solutions that would allow rapid response.
      • Technology
      • In spite of past innovations in technologies such as microfluidics to help with miniaturization, truly portable molecular diagnostics systems have largely eluded us due to lack of compact opto-electronic instrumentation.

        We strive to solve this problem by introducing ultra low-light CMOS biosensors (e.g. Anitoa ULS24) that are highly sensitive and integrated, yet low cost to replace the bulky and expensive PMTs and CCDs in today's molecular testing instruments, to achieve portability.

      • Anitoa ULS24 CMOS biosensor eco system includes mobile and cloud-based software interface and analytics
      • Applications of Anitoa Ultra low-light CMOS Biosensor
        DNA and RNA quantification, fluorescent-based
        Miniaturized qPCR, microfluidic qPCR, and digital PCR
        Fluorescence or chemiluminescence-based Immunoassay/ELISA
        DNA or Protein microarray
        Capillary electrophoresis
        Cell sorting/Imaging flow cytometry
        Fluorescence Images Guided Surgery (FIGS)

      • Anitoa ULS24 CMOS biosensor applied in qPCR to successfully detect E Coli. (DH5a), HBV (wild type and rtM2041), and foot-and-mouth disease (EV71 and CA16).

    • White papers and Application notes

    • Click here to download a White paper on Anitoa's CMOS biosensor innovation (short version or long version).

    • Application Note: How to integrate ULS24 in an embedded system.

    • Application Note: Different options of adding optics to ULS24.

    • Application Note: How to perform temperature compensated dark subtraction in ULVision.

    • Application Note: Quantum dot applications in fluorescence imaging – calibration and molecular imaging.

    • Application Note: DNA quantification with Anitoa's CMOS-based fluorescence imager.

    • Application Note: Using ULS24 as the read-out sensor for Chemiluminescence Immunoassay.

    • Publication: Ultra-low-Light CMOS Biosensor Complements Microfluidics to Achieve Portable Diagnostics. Procedia Technology (c)2017 Elsevier BV

    • 3rd Party Publication: Bioluminescent bioreporter pad biosensor for monitoring water toxicity. (c)2015 Elsevier BV